Biomineralized and Stimuli Responsive Hydrogel for Biomedical Applications

Anotace

In the last decade, tissue engineering and regenerative medicine actively focus on scaffolds which have a three dimensional structure for a better regeneration of tissue. Depending on the type of regeneration needed, the scaffolds can be prepared for both hard and soft tissues. Hard tissues are basically represented by bone composites containing organic matrix reinforced by inorganic minerals in the form of a hybrid structure. A relatively new concept in the development of scaffolds for the hard tissues is the formation of Biomimicry formed in the matrix through biomineralization. In these cases, the matrix is mostly represented by a biomaterial in which the crystal structure of minerals grows. From many available biomaterials hydrogels are preferred especially due to their ability to store large amount of liquid and create environment favourable for regeneration of living tissue.